Korean J Anesthesiol.  2003 Aug;45(2):205-209. 10.4097/kjae.2003.45.2.205.

The Effect of Epidural Butorphanol for Analgesia after Cesarean Section

• Ji JN
• Kim YH
• Shin YS

• KMID: 2236716
• DOI: http://doi.org/10.4097/kjae.2003.45.2.205

Abstract

BACKGROUND: This study aimed to compare analgesic efficacy and the side effects of postoperative continuous epidural infusion (2 ml/hr) of morphine (40 microgram/ml) or butorphanol (50 microgram/ml) administered with 0.15% ropivacaine 100 ml.
METHODS
Forty consenting, healthy, term parturients who had undergone Ceasarean section under epidural lidocaine and ropivacaine anesthesia received a morphine 1 mg bolus and 0.15% ropivacaine 100 ml/morphine 4 mg (Group M, n = 20) or a butorphanol 2 mg bolus and 0.15% ropivacaine 100 ml/butorphanol 5 mg (Group B, n = 20) using an epidural 2 day infuser (2 ml/hr) 30 minutes after surgical incision.
RESULTS
No significant difference were observed by the visual analog scale (VAS) for pain during rest, but Group B requested significantly greater amounts of supplementary diclofenac sodium during the first 24 hours. Side effects were higher in pruritus in Group M and in somnolence in Group B, but no significant differences in severe side effects were evident between the two groups.
CONCLUSIONS
Using 0.15% ropivacaine 100 ml with morphine (40 microgram/ml) via an epidural 2 day infuser (2 ml/hr) provided better pain relief than butorphanol (50 microgram/ml) group, but significant side effects, such as pruritus, were observed.

Keyword

analgegics; butorphanol; morphine; postoperative pain

MeSH Terms

Analgesia*
Anesthesia
Butorphanol*
Cesarean Section*
Diclofenac
Female
Lidocaine
Morphine
Pain, Postoperative
Pregnancy
Pruritus
Visual Analog Scale
Butorphanol
Diclofenac
Lidocaine
Morphine