Korean J Anesthesiol.  1998 Jan;34(1):126-131. 10.4097/kjae.1998.34.1.126.

Comparison of Butorphanol and Fentanyl Administered with Bupivacaine for Patient Controlled Epidural Analgesia after Cesarean Section

• Kim DH
• Kim TJ
• Park NH

• KMID: 2032354
• DOI: http://doi.org/10.4097/kjae.1998.34.1.126

Abstract

BACKGROUND
For the efficacy of pain relief, the adequate infusion dosage and the side effects of epidural butorphanol was compared with those of epidural fentanyl.
METHODS
Forty consenting, healthy, term parturients who had undergone Caesarean section under epidural lidocaine anesthesia received 0.1% bupivacaine/ butorphanol 50 ug/ml (Group 1, n=20) or 0.1% bupivacaine/fentanyl 5 ug/ml (Group 2, n=20) using patient controlled epidural analgesia (PCEA) were evaluated.
RESULTS
Total amount of 48hr consumption was 19.4 mg (butorphanol) and 1546.8 ug (fentanyl). There were no significant differences between two groups in total infusion doses of above drugs, VAS score and side effects. The putative potency ratio of fentanyl/butorphanol was 1/12.5.
CONCLUSIONS
Although both butorphanol and fentanyl were useful and safe drug for PCEA for postoperative pain control, combination of butorphanol and bupivacaine provided more economically effective analgesia.

Keyword

Analgesia: patient-controlled; postoperative; Analgesics: butorphanol; epidural; fentanyl; Anesthetics, local: bupivacaine

MeSH Terms

Analgesia
Analgesia, Epidural*
Anesthesia
Bupivacaine*
Butorphanol*
Cesarean Section*
Female
Fentanyl*
Humans
Lidocaine
Pain, Postoperative
Pregnancy
Bupivacaine
Butorphanol
Fentanyl
Lidocaine