Korean J Dermatol.  1978 Aug;16(4):325-329.

A Case of Gout Accompanied by Tophi

• Kim YT
• Kim JH

Abstract

Gout is not very rare disorder in high economic countries and it is seldom observed in our country and is hard to find its report in Korean dermatologic literature. Gout is a disease of inbom metabolic and/or acquired form of the disease chara-cterized by hyperuricemia, tophaceous deposits of sodium urate and recurrent attacks of arthrit.is which dramatically responds to Colchine. A case of tophaceous gout in a 56 year old Korean male is reported. The patient showed pea to waInut size, yellowish tender subcutaneous masses on right great toe and both solee of 15 year duration which are adherented to the overIying skin. The hiatology of the lesion revealed variously sized, sharply demarcated aggregates of needle shaped urate crystals in bund.his and sheaves which are surrounded by fibrous connective tissue which are in tum surrounded by granulomatous infiltrate containing small round cells and foreign body glant cells. The urate crystals have a brownish color and are doubly refractile on polariscopic examination. The use of colchine, in a initial dose of 1mg foIIowed by 0. 5mg every hour for 6 hours. The patient failed to attend the clinic regularly and was lost for folIow up.

MeSH Terms

Connective Tissue
Foreign Bodies
Gout*
Humans
Hyperuricemia
Male
Middle Aged
Needles
Peas
Skin
Toes
Uric Acid
Uric Acid