Korean J Dermatol.  1985 Apr;23(2):204-208.

Cyclosporin Modulates DNCB Contact Hypersensitivity Reaction in Guinea Pigs

• Jo I
• Houh W

Abstract

CsA per os during the early sensitization period caused potentiation of 14-day shin response and this response was enhanced in group D, CsA given on days 3 7 Thereafter, suppression of CHS began in group E, CsA was given on days 6- 1G, and this tendency continue to the time of full sensitization of guinea pigs (group G). 27701173 We report herein a case of alopecia mucinosa in a 46-year-old male. He had a coin-sized erythematous hairless plaque on the parietal area. Histopathologic examinations, including much stains, showed typical findings of alopecia mucinosa. Thc present case, appeared on the scalp, might be an acute benign type of the disease.

Keyword

Cyclosporin A (CsA); Dinitrochlorobenzene (DNCB); Contact hypersensitivity (CHS)

MeSH Terms

Animals
Coloring Agents
Cyclosporine*
Dermatitis, Contact*
Dinitrochlorobenzene*
Dronabinol
Guinea Pigs*
Guinea*
Humans
Male
Middle Aged
Mucinosis, Follicular
Rabeprazole
Scalp
Coloring Agents
Cyclosporine
Dinitrochlorobenzene
Dronabinol