Korean J Dermatol.  1987 Oct;25(5):629-632.

Vitiliginous Hypopigmented Patches Developed during Photochemotherapy ( PUVA ) in a patient with Psoriasis

• Park YK
• Song DH
• Kim HJ

Abstract

We observed a 51-year-old male, who developed depigmented patches on the lower abdomen after photochemotherapy(PUVA) of psoriasis without evidence of phototoxic reaction. The depigmented patches did not orginate from the sites of previous psoriatic lesions. Fontana-Masson stain of the biopsy specimen revealed nearly absent melanin pigments in the epidrmis of the hypopigmented patch, while lots of pigments were obsereved on the surrounding hyperpigmented area. Electron micrograph showed no melanocytes in the hypopigmented patch. Thus we report this case as having vitiliginous patches induced by photochemotherapy of psoriasis.

Keyword

Vitiligo; PUV ; Psoriasis

MeSH Terms

Abdomen
Biopsy
Humans
Male
Melanins
Melanocytes
Middle Aged
Photochemotherapy*
Psoriasis*
Vitiligo
Melanins