Korean J Crit Care Med.  2013 May;28(2):152-155. 10.4266/kjccm.2013.28.2.152.

A Case of Functioning Paraganglioma Mimicking Anaphylactic Shock: A Case Report

Affiliations
  • 1Department of Internal Medicine, Division of Endocrinology and Metabolism, Inha University School of Medicine, Incheon, Korea. sbhongmd@inha.ac.kr
  • 2Department of Emergency Medicine, Inha University School of Medicine, Incheon, Korea.

Abstract

Paraganglioma is a tumor originating from the extra-adrenal chromaffin cells, and functional paraganglioma causes paroxysmal hypertension, headache and tachycardia, due to excess excretion of catecholamine. However, rarely, ARDS, acute myocardial infarction, heart failure, arrhythmia, and pulmonary edema are also seen in patients with paraganglioma and clinical manifestations are depending on the patient's intravascular volume status. Seventy one-years-old male was presented with hypotension and pulmonary edema after intravenous midazolam injection during colonoscopy under conscious sedation. The patient was initially suspected with anaphylactic shock, due to midazolam injection. However, later, he was diagnosed with paraganglioma, and blood pressure was successfully controlled with alpha adrenergic blockade. We suggest that when we encounter heart failure, pulmonary edema and shock of unknown origin, pheochromocytoma must be taken into consideration.

Keyword

midazolam; paraganglioma; shock

MeSH Terms

Anaphylaxis
Arrhythmias, Cardiac
Blood Pressure
Chromaffin Cells
Colonoscopy
Conscious Sedation
Headache
Heart Failure
Humans
Hypertension
Hypotension
Male
Midazolam
Myocardial Infarction
Paraganglioma
Pheochromocytoma
Pulmonary Edema
Shock
Tachycardia
Midazolam
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