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Epidemiology and Prognosis of Pheochromocytoma/Paraganglioma in Korea: A Nationwide Study Based on the National Health Insurance Service

Kim JH, Moon H, Noh J, Lee J, Kim SG

BACKGROUND: Pheochromocytomas and paragangliomas (PPGLs) are rare endocrine tumors originating from chromaffin cells. PPGLs are associated with a high mortality rate and several complications. To date, no epidemiological studies have...
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Malignant Gastric Paraganglioma with Liver Metastasis: Imaging Findings and Literature Review

Kim YR, Lee YH, Yun KJ

Paraganglioma is a neuroendocrine tumor that grows in organs other than the adrenal gland and typically originates in the chromaffin cells, which are distributed along the regions of the sympathetic...
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Melatonin inhibits nicotinic acetylcholine receptor functions in bovine chromaffin cells

Jo SH, Lee SH, Kim KT, Choi SY

Melatonin is a neurotransmitter that modulates various physiological phenomena including regulation and maintenance of the circadian rhythm. Nicotinic acetylcholine receptors (nAChRs) play an important role in oral functions including orofacial...
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Acute Aortic Dissection in a Patient with Pheochromocytoma

Lee SJ, Jang HJ, Lee YH, Lee JE, Lee YC

Pheochromocytomas are neoplasms of the adrenal gland that are derived from chromaffin cells. One of the most important features of this tumor is that it can synthesize and release catecholamines...
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Imaging Findings of a Primary Paraganglioma of the Liver: A Case Report

Ji SW, Kang UR, Park JB

Primary hepatic paraganglioma is an extremely rare type of tumor originating from extra-adrenal chromaffin cells. We report a case of primary intrahepatic paraganglioma in a 52-year-old man, with pathologic confirmation...
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A Case of Pheochromocytoma Initially Manifesting as Acute Myocardial Infarction

Chae SS, Kang JT, Ahn YK, Hong R, Kim JW

Pheochromocytomas are rare catecholamine-secreting neuroendocrine tumors arising from chromaffin cells in the adrenal medulla. Typical classic triad are consisted of headaches, palpitations, and profuse diaphoresis. But some patients with pheochromocytomas...
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A New Approach to the Treatment of Metastatic Paraganglioma: Sorafenib

Gunaldi M, Kara IO, Duman BB, Afsar CU, Ergin M, Avci A

Paragangliomas are relatively rare chromaffin cell tumors which may be cured through resection. Patients with paragangliomas may develop metastatic diseases. There is no consensus regarding refractory chemotherapy for treatment of...
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Inhibitory Effects of Ginsenoside-Rb2 on Nicotinic Stimulation-Evoked Catecholamine Secretion

Lim HJ, Lee HY, Lim DY

The aim of the present study was to investigate whether ginsenoside-Rb2 (Rb2) can affect the secretion of catecholamines (CA) in the perfused model of the rat adrenal medulla. Rb2 (3~30...
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A Case Report of Recurrent Malignant Paraganglioma with Lung and Spine Metastasis that Occurred Sixteen Years after Primary Tumor Excision

Moon ES, Min HS, Jung CH, Choi JH, Kim JS, Yoo HJ, Choi SY

Paragangliomas are rare tumors that arise from the extra-adrenal chromaffin cells, and malignancy is defined by the presence of metastases to sites that normally lack chromaffin tissue. The main therapeutic...
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Effect of ATP on Calcium Channel Modulation in Rat Adrenal Chromaffin Cells

Kim KA, Goo YS

ATP in quantity co-stored with neurotransmitters in the secretory vesicles of neurons, by being co-released with the neurotransmitters, takes an important role to modulate the stimulus-secretion response of neurotransmitters. Here,...
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A Case of Pheochromocytoma Associated with Diabetic Ketoacidosis and Infective Endocarditis

Bae JH, Choe EY, Huh JH, Moon DC, Shin SH, Kim KJ, Lee BW, Ahn CW, Cha BS, Lee HC, Kang ES

Pheochromocytoma is a rare neuroendocrine tumor that is usually derived from adrenal medulla or chromaffin cells along with sympathetic ganglia. In Western countries, the prevalence of pheochromocytoma is estimated to...
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A Case of Functioning Paraganglioma Mimicking Anaphylactic Shock: A Case Report

Han JY, Lee OH, Kim GE, Han SB, Kim SH, Nam M, Kim YS, Hong S

Paraganglioma is a tumor originating from the extra-adrenal chromaffin cells, and functional paraganglioma causes paroxysmal hypertension, headache and tachycardia, due to excess excretion of catecholamine. However, rarely, ARDS, acute myocardial...
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Influence of PD 123319 (AT2-Receptor Antagonist) on Catecholamine Secretion in the Perfused Rat Adrenal Medulla

Hong SP, Bidur B, Choi MS, Seo YH, Lim DY

BACKGROUND: The aim of this study was to examine whether PD 123319 (an angiotensin II type 2 [AT2] receptor antagonist) can influence the release of catecholamines (CA) from the perfused...
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Influence of Fimasartan (a Novel AT1 Receptor Blocker) on Catecholamine Release in the Adrenal Medulla of Spontaneously Hypertensive Rats

Lim HJ, Lee SK, Lim DY

The aim of this study was to determine whether fimasartan, a newly developed AT1 receptor blocker, can affect the CA release in the isolated perfused model of the adrenal medulla...
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Mechanism of Interdigestive Migrating Motor Complex

Takahashi

  • KMID: 2325917
  • J Neurogastroenterol Motil.
  • 2012 Jul;18(3):246-257.
Migrating motor complex (MMC) is well characterized by the appearance of gastrointestinal contractions in the interdigestive state. This review article discussed the mechanism of gastrointestinal MMC. Luminal administration of 5-hydroxytryptamine...
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A Case of Dopamine-Secreting Pheochromocytoma

Park JK, Oh HK, Shon MH, Kim HH, Jeon EJ, Jung ED

A pheochromocytoma is a neuroectodermal tumor that originates from the chromaffin cells of the sympathetic system. It has typical symptoms or signs, such as periodic attacks of paroxysmal hypertension, palpitation,...
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Serotonin Outside the Central Nervous System

Song HR, Woo YS, Bahk WM

  • KMID: 2287470
  • Korean J Psychopharmacol.
  • 2012 Apr;23(2):45-50.
Most serotonin is found outside the central nervous system and functions much more than a neurotransmitter. Peripheral serotonin is produced by enterochromaffin cells in the gastrointestinal tract and secreted into...
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Laparoscopically Resected Composite Pheochromocytoma-Ganglioneuroma

Kim NR, Kim T, Lee JN, Eom YS, Chung DH, Park S, Cho HY

Composite pheochromocytoma-ganglioneuroma is one of the mixed neuroendocrine-neural tumors composed of pheochromocytoma and other neural crest derivatives. To date, less than 50 cases of composite pheochromocytoma have been reported, and...
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Flushing in a Young Woman: Skin Manifestation of Carcinoid Syndrome

Sim JH, Lee GH, Kim HD, Lee SY, Park YL, Whang KU

  • KMID: 2247529
  • Korean J Dermatol.
  • 2011 Nov;49(11):1006-1009.
Carcinoid tumors are derived from enterochromaffin cells that are capable of producing a wide range of neuroendocrine mediators including serotonin or 5-hydroxytryptamine. Carcinoid syndrome occurs when mediators produced by the...
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Changes of colonic endocrine cells in trinitrobenzene sulfonic acid (TNBS)-induced rat colitis

Back YD, Lee HS, Chung IK, Cheon WH, Ku SK

  • KMID: 1446199
  • Korean J Vet Res.
  • 2011 Jun;51(2):83-91.
In this study, immunohistochemistry was used to examine the changes in the density of colonic endocrine cells - argyrophil and argentaffin cells, chromogranin A (CGA), serotonin, somatostatin and glucagon-containing cells...
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