Korean J Clin Pharm.  2015 Dec;25(4):264-272. 10.0000/kjcp.2015.25.4.264.

Analysis of Healthcare Personnel's Clinical Beliefs and Knowledge behind Overutilization of Stress Ulcer Prophylaxis in Hospitalized Patients

• Noh Y
• Lee JM
• Shin S

• KMID: 2226420
• DOI: http://doi.org/10.0000/kjcp.2015.25.4.264

Abstract

BACKGROUND
The over-prescription of acid-suppressive therapy for the provision of stress ulcer prophylaxis (SUP) in hospitalized patients has been identified in a proceeding study.
OBJECTIVE
This study was conducted to evaluate clinicians' beliefs, knowledge and other factors that influence the over-prescribing of SUP in low-risk, non-intensive care unit (non-ICU) patients. METHOD: A cross-sectional survey consisting of multiple-choice queries and close-ended questions was distributed to healthcare personnel at a major teaching hospital in Korea.
RESULTS
More than half of total respondents reported that they would continue SUP following patients discharge from the ICU (77.8%, 43.5%, and 39.7% in the physician, pharmacist, and nurse groups, respectively). Over 55% of physicians would also initiate non-ICU patients on SUP upon hospital admission, and 42.6% of physicians would even continue prophylaxis post hospital discharge. The mean knowledge score regarding SUP indications and side effects was higher in pharmacists compared to physicians and nurses (12.44, 7.40, and 7.28, respectively; p<0.001). High-prescribing behavior was associated with a prescriber's belief that SUP is effective for preventing bleeding (odds ratio 7.40; 95% confidence interval 1.57 to 31.94; p=0.012). Low knowledge score and computerized order set also showed statistically significant association with the overutilization of SUP.

Keyword

proton pump inhibitor; histamine-2-receptor antagonist; stress ulcer prophylaxis; gastrointestinal bleeding

MeSH Terms

Cross-Sectional Studies
Surveys and Questionnaires
Delivery of Health Care*
Hemorrhage
Hospitals, Teaching
Humans
Korea
Pharmacists
Ulcer*