Korean Circ J.  2010 Jul;40(7):348-351. 10.4070/kcj.2010.40.7.348.

Fatal Renal Bleeding in a Patient Treated With Aggressive Antithrombotic Therapy After Recurrent Coronary Stent Thrombosis

Affiliations
  • 1Cardiology Division, Department of Internal Medicine, Severance Cardiovascular Hospital, Seoul, Korea. shl1106@yuhs.ac
  • 2Department of Urology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Triple antiplatelet therapy has been known to be superior to the conventional dual regimen for preventing stent thrombosis after coronary stenting, and the addition of oral anticoagulation to antiplatelet therapy is also considered an option. However, the risks and benefits of a triple antiplatelet regimen plus additional oral anticoagulation must be taken into account. Here, we report a case of fatal renal bleeding in a patient treated with triple antiplatelet plus oral anticoagulant therapy for the prevention of recurrent stent thrombosis.

Keyword

Drug-eluting stents; Coronary thrombosis; Drug combinations

MeSH Terms

Coronary Thrombosis
Drug Combinations
Drug-Eluting Stents
Hemorrhage
Humans
Risk Assessment
Stents
Thrombosis
Drug Combinations

Figure

  • Fig. 1 Coronary angiographies taken at each event (RCA). A: stent thrombosis and partial obstruction in the RCA (arrow) in July 2008. B: RCA revascularized by thrombosuction and implantation of new stents. C: recurrent stent thrombosis and partial obstruction (arrow) in August 2008. D: lesion revascularized by thrombosuction. E: recurrent stent obstruction (arrow) in September 2008. F: lesion treated by repeated thrombosuction and new stent implantation.

  • Fig. 2 Abdominal CT. Massive hemorrhage in left kidney (arrow).


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