Korean Circ J.  2011 Nov;41(11):681-684. 10.4070/kcj.2011.41.11.681.

Type 2 Myocardial Infarction Following Generalized Tonic-Clonic Seizure

  • 1Division of Cardiology, Department of Internal Medicine, Hanyang University Medical Center, Seoul, Korea. jhs2003@hanyang.ac.kr
  • 2Division of Cardiology, Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea.


Myocardial infarction is diagnosed when blood levels of biomarkers are increased in the clinical setting of acute myocardial ischemia. Among the biomarkers, troponin I is the preferred biomarker indicative of myocardial necrosis. It is tissue specific for the heart. Myocardial infarction is rarely reported following seizure. We report a case of elevated troponin I in a patient after an episode of generalized tonic-clonic seizure. The diagnosis was type 2 myocardial infarction.


Epilepsy; Myocardial infarction; Troponin I; Coronary angiography

MeSH Terms

Coronary Angiography
Myocardial Infarction
Myocardial Ischemia
Troponin I
Troponin I


  • Fig. 1 Fluid attenuated inversion recovery brain magnetic resonance image. This showed high signal intensity around a previous hemorrhage site in the left frontal lobe, indicating malatic change after hemorrhage without evidence of newly developed lesions.

  • Fig. 2 Computed tomography for coronary artery showing more than 50% stenosis of the middle left anterior descending artery (white arrow).

  • Fig. 3 Coronary angiography showed 30% stenosis in the middle left anterior descending artery in the left lateral oblique cranial view (white arrow) (A) and there was no stenosis of the right coronary artery (B).


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