J Rheum Dis.  2011 Dec;18(4):276-282. 10.4078/jrd.2011.18.4.276.

Uveitis and Rheumatic Diseases in a Community Based Practice - Korean Population

• Kim NK
• Park MY
• Lee JH
• Lee DH
• Yoon BY

• KMID: 2223130
• DOI: http://doi.org/10.4078/jrd.2011.18.4.276

Abstract

OBJECTIVE
We aimed to investigate the frequency of rheumatic diseases within uveitis patients visiting the department of Ophthalmology and evaluated the clinical value of serological testing and ophthalmologic findings in patients with uveitis in a community-based practice in Korean population.
METHODS
On a retrospective basis, we reviewed the medical records of patients with uveitis, who had been treated at the Department of Ophthalmology of Inje University Ilsan Paik Hospital between January 2005 and March 2010. All patients with uveitis were reviewed regarding their ocular histories and findings, rheumatologic medical histories and manifestations, and pelvis anteroposterial view of plain radiographies to identify the sacroilitis. In addition, we tested for rheumatoid factor, antinuclear antibody, and HLA-B27.
RESULTS
A total of 107 patients with uveitis were included in the study. HLA-B27 associated uveitis was present in 64 patients (59.8%) the number of patients with sacroilitis on plain pelvis radiography was 38 patients (37.8%). Fifty-one patients (47.7%) were diagnosed as having systemic rheumatic diseases. The majority of these patients had anklylosing spondylitis (AS) (70.3%) and Bechet's disease (18.9%). The most common type of uveitis was anterior uveitis (90.7%), followed by panuveitis (3.7%) and posterior uveitis (3.7%). The recurrence rate and number of floating cells were greater in patients with rheumatic diseases than patients without rheumatic diseases.
CONCLUSION
The majority of rheumatic disease related with uveitis were AS and Bechet's disease. HLA-B27 and pelvis plain radiography can be useful tools for screening the spondyloarthropathies with uveitis. Recurrent and severe uveitis might represent an accompanying rheumatic disease.

Keyword

Uveitis; HLA-B27; Spondyloarthropathy; Sacroiliitis

MeSH Terms

Antibodies, Antinuclear
HLA-B27 Antigen
Humans
Mass Screening
Medical Records
Ophthalmology
Panuveitis
Pelvis
Recurrence
Retrospective Studies
Rheumatic Diseases
Rheumatoid Factor
Sacroiliitis
Serologic Tests
Spondylarthropathies
Spondylitis
Uveitis
Uveitis, Anterior
Uveitis, Posterior
Antibodies, Antinuclear
HLA-B27 Antigen
Rheumatoid Factor

Reference

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