J Rheum Dis.  2014 Feb;21(1):46-49. 10.4078/jrd.2014.21.1.46.

Acute Precursor T Cell Lymphoblastic Leukemia Associated with Behcet's Disease: A Case Report

Affiliations
  • 1Division of Rheumatology, Department of Internal Medicine, Korea University Medical College, Seoul, Korea. lyhcgh@korea.ac.kr

Abstract

Behcet's disease is an inflammatory disorder characterized by recurrent oral aphthous ulcers, genital ulcers, uveitis, and skin lesions. A few cases of hematologic disease in patients with Behcet's disease have been reported in the literature. However, acute precursor T cell lymphoblastic leukemia has never been described in association with Behcet's disease. We recently encountered a case of acute precursor T cell lymphoblastic leukemia in a 62-year-old man with a prior diagnosis of Behcet's disease. The patient presented with febrile neutropenia and his bone marrow biopsy revealed acute precursor T cell lymphoblastic leukemia. He was scheduled to undergo therapeutic chemotherapy, but unfortunately he died from pneumonia prior to treatment.

Keyword

Behcet's disease; Acute precursor T cell lymphoblastic leukemia

MeSH Terms

Biopsy
Bone Marrow
Diagnosis
Drug Therapy
Febrile Neutropenia
Hematologic Diseases
Humans
Middle Aged
Pneumonia
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma*
Skin
Stomatitis, Aphthous
Ulcer
Uveitis
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