J Korean Ophthalmol Soc.  2013 Jul;54(7):1104-1108. 10.3341/jkos.2013.54.7.1104.

Muscle Weakening and Change of Tension According to Degree of Superior Rectus Z-Myotomy in Rabbits

• Kim SY
• Lee YC

• KMID: 2217423
• DOI: http://doi.org/10.3341/jkos.2013.54.7.1104

Abstract

PURPOSE
To identify the muscle weakening effect and the change of muscle tension according to degree of superior rectus Z-myotomy in rabbits.
METHODS
After dissection of superior rectus in 15 rabbits (30 eyes), marking was done on 10 mm apart from muscle insertion. Then, Z-myotomy was done on 2 mm and 8 mm apart from muscle insertion which are two different positions on apposite sides. 25%, 50% and 75% Z-myotomy were defined as group 1 (10 eyes), group 2 (10 eyes) and group 3 (10 eyes). After Z-myotomy, the change of muscle lengthening between muscle insertion and marking, and muscle tension were measured. At 4 weeks after Z-myotomy, all parameters were re-measured.
RESULTS
After Z-myotomy all markings moved posteriorly, and showed result as 10.83 +/- 0.13 mm in group 1, 11.02 +/- 0.17 mm in group 2 and 12.01 +/- 0.23 mm in group 3 respectively. Muscle tension result showed as 3.98 +/- 0.22 mm in group 1, 3.54 +/- 0.18 mm in group 2 and 2.87 +/- 0.25 mm in group 3. In comparison of three groups, group 2 and group 3 showed the significant results (p < 0.05). At 4 weeks after Z-myotomy the markings showed result as 10.55 +/- 0.14 mm, 10.85 +/- 0.20 mm, 11.91 +/- 0.14 mm respectively, and in group 2 and group 3 the significant changes were seen (p < 0.05). Muscle tensions were 4.01 +/- 0.31 mm, 3.88 +/- 0.53 mm, 3.12 +/- 0.42 mm respectively. There were significant results in group 2 and group 3 (p < 0.05).
CONCLUSIONS
75% Z-myotomy of superior rectus showed significant results in muscle weakening and decreasing muscle tension.

Keyword

Muscle weakening; Z-myotomy

MeSH Terms

Muscle Tonus
Muscles
Rabbits

Figure

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  Figure 1. Photographs of superior rectus according to the degree of Z-myotomy. (A) 25% Z-myotomy of muscle width. (B) 50% Z-myotomy of muscle width. (C) 75% Z-myotomy of muscle width.

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  Figure 2. Histologic findings of Z-myotomy site (75% Z-my-otomy of muscle width) at 4 weeks after surgery (Masson’s tri-chrome stain). Distorted muscle structures and collagen fiber proliferations (arrows) between muscle fibers were shown.

Reference

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