Korean J Ophthalmol.  1994 Jun;8(1):14-19. 10.3341/kjo.1994.8.1.14.

Pathologic changes after inferior oblique marginal myotomy in rabbits

Affiliations
  • 1Department of Ophthalmology, Korea Veterans Hospital, Seoul, Korea.

Abstract

To evaluate the histopathologic changes after an inferior oblique marginal myotomy with local injection of triamcinolone, an inferior oblique marginal myotomy was performed in 14 white rabbits and they were divided into 2 groups, one group with a local injection of triamcinolone and the other group without triamcinolone injection after a myotomy. At the postoperative one month, an edema of the muscle fibers and an infiltration of the inflammatory cells were observed and at postoperative three months, a fibrous tissue ingrowth around the muscle fibers and an atrophy of the muscle fibers were found and those changes were less prominant in the group with triamcinolone injection. The local injection of triamcinolone after the inferior oblique marginal myotomy would help in decreasing the fibrous tissue ingrowth and the formation of the scar tissue, thus it could be used in augmenting the effect of the inferior oblique marginal myotomy.

Keyword

inferior oblique marginal myotomy; triamcinolone; histopathologic changes; inflammatory reactions; fibrous tissue infiltration

MeSH Terms

Animals
Atrophy
Edema
Eye Diseases/pathology
Injections
Oculomotor Muscles/drug effects/*pathology/*surgery
Rabbits
Triamcinolone/administration & dosage
Triamcinolone
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