J Korean Surg Soc.
2006 Apr;70(4):321-324.
Composite Neuroendocrine Carcinoma with Adenocarcinoma of the Stomach Mimicking Double Primary Cancer
- Affiliations
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- 1Department of Surgery, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea. ypcho@gnah.co.kr
- 2Department of Diagnostic Pathology, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea.
- 3Department of Diagnostic Radiology, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea.
- 4Department of Internal Medicine, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea.
Abstract
- A 67-year-old man presented with a 3-month history for intermittent epigastric pain and postprandial discomfort. Upper gastrointestinal endoscopy and contrast-enhanced axial computed tomographic scan demonstrated two separate tumors of the gastric antrum and the duodenal second portion, suggestive of the preoperative diagnosis of a double primary cancer. Pancreaticoduodenectomy with lymph node dissection was performed, and the microscopic features and immunohistochemical profiles of the resected specimen confirmed the diagnosis of the composite neuroendocrine carcinoma with adenocarcinoma of the stomach (mixed exocrine-endocrine carcinoma).
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