J Korean Ophthalmol Soc.  2002 Sep;43(9):1605-1611.

Clinical Outcomes of Penetrating Keratoplasty and Limbal Transplantation from the Same Versus Different Donor Graft

• Kim MK
• Lee JL
• Wee WR
• Lee JH

Abstract

PURPOSE: To evaluate the difference of the central graft rejection after penetrating keratoplasty and limbal allograft transplantation from different donors vs from the same donor. MATERIAL and METHODS: Three patients diagnosed with chemical burn and one with Stevens-Johnson syndrome were included. Three patients underwent penetrating keratoplasty and limbal allograft transplantation from different donors and one underwent the same operation from the same donor. Mean follow-up was 13 months. Visual acuity, re-epithelization and endothelial rejection were examined.
RESULTS
Re-epithelization occurred within 3 to 14 days (mean 8.7 days) in three eyes with chemical burn. Visual acuities ranged from light perception to 20/100. Endothelial rejection developed in the eye transplanted from the same donor. Re-epithelization failed in the eye with Stevens-Johnson syndrome even though limbal graft transplantation and cultivated limbal epithelium transplantation were performed repeatedly.
CONCLUSIONS
Corneal endothelial rejection seemed to decrease after penetrating keratoplasty and limbal allograft transplantation from different donors.

Keyword

Limbal allograft transplantation; Penetrating keratoplasty; Different donors; Same donors; Endothelial rejection

MeSH Terms

Allografts
Burns, Chemical
Epithelium
Follow-Up Studies
Graft Rejection
Humans
Keratoplasty, Penetrating*
Stevens-Johnson Syndrome
Tissue Donors*
Transplants*
Visual Acuity