J Korean Ophthalmol Soc.  1992 Feb;33(2):109-113.

Measurement of Transendothelial Potential Difference to Evaluate the Chondroitin Sulfate Effect in TC-l99 Cornea Preservation Media

• Lee HB

Abstract

Chondroitin sulfate (CS) in corneal preservation medium can porolong corneal preservation time. The solutions used in the experimental chambers were made of TC-199 (GIB Co.) either by itself of by adding 1% CS (Sigma) to the TC-199. The evaliation of the viability of corneas can be made by monitoring their physiological parameter. Thus, we monitored the transendothelial electrical potential difference (p.d.) across deepithelialized rabbit corneas. We found that TC-199 containing 1% CS maintained higher p.d.'s than the same solution without CS.

Keyword

Chondroitin sulfate; Corneal preservation; Electrical potential difference; TC-199

MeSH Terms

Chondroitin Sulfates*
Chondroitin*
Cornea*
Chondroitin
Chondroitin Sulfates