J Korean Soc Plast Reconstr Surg.  2002 May;29(3):218-220.

Malignant Hyperthermia under General Anesthetic Operation: A Case Report

• Kim C
• Bae IH
• Seo YM
• Chang SC

Abstract

Malignant hyperthermia is an inherited disorder of skeletal muscle, characterized by temperature elevation, muscle destruction, muscle rigidity and high oxygen consumption. It is triggered by anesthetic agents, usually potent inhalation anesthetics and succinylcholine. It is fatal in the majority of cases unless early diagnosis and treatment are performed. We experienced one case of malignant hyperthermia incidentally. She had post burn scar contracture on anterior chest and abdomen and local flap was prepared for releasing scar contracture under general anesthesia. Approximately 3 hours after induction, tachycardia developed followed by severe arrhythmia with unstable blood pressure, temperature elevation and cyanosis. Anesthesia was stopped immediately and aggressive emergency management was performed with Dantrolene. About 4 hours after induction, the patient was recovered to normal state with intensive care.

Keyword

Malignant hyperthermia; General anesthesia; Dantrolene

MeSH Terms

Abdomen
Anesthesia
Anesthesia, General
Anesthetics
Anesthetics, Inhalation
Arrhythmias, Cardiac
Blood Pressure
Burns
Cicatrix
Contracture
Cyanosis
Dantrolene
Early Diagnosis
Emergencies
Humans
Critical Care
Malignant Hyperthermia*
Muscle Rigidity
Muscle, Skeletal
Oxygen Consumption
Succinylcholine
Tachycardia
Thorax
Anesthetics
Anesthetics, Inhalation
Dantrolene
Succinylcholine