J Korean Soc Clin Neurophysiol.
2012 Jun;14(1):36-40.
Nephrogenic Systemic Fibrosis with Myopathy
- Affiliations
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- 1Department of Neurology, Soonchunhyang University College of Medicine, Seoul, Korea. newroh@schmc.ac.kr
- 2Department of Pathology, Soonchunhyang University College of Medicine, Seoul, Korea.
Abstract
- Nephrogenic systemic fibrosis (NSF) is a systemic disease that affects the skin and other tissues in patients with renal insufficiency and exposure to gadolinium-containing contrast. A 55-year-old woman with end-stage renal disease on hemodialysis was consulted for progressive general weakness. After she had undergone multiple MRIs with gadolinium-containing contrast media, muscle weakness and skin lesions were developed. Her skin and muscle biopsy specimens showed CD34+ fibroblast entrapping collagen bundles. There are few reports of NSF with myopathy.
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