Ann Rehabil Med.
2012 Dec;36(6):880-886.
A Case of Delayed Onset Nephrogenic Systemic Fibrosis After Gadolinium Based Contrast Injection
- Affiliations
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- 1Department of Physical and Rehabilitation Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea. hwanglee@skku.edu
- 2Department of Rehabilitation Medicine, Pusan National University Yangsan Hospital, Yangsan 602-739, Korea.
Abstract
- Nephrogenic systemic fibrosis (NSF) is a rare fibrosing disorder of the skin and joints that occurs in patients with advanced renal insufficiency. This condition is progressive and can be seriously disabling. Gadolinium based contrast agent (GBCA) has been identified as a potential cause of this condition. A 56-years-old man in hemodialysis developed stiffness and contracture of the whole limbs eight years after frequent GBCA exposure for cervical magnetic resonance imaging. For the first time in Korea, we report late-onset nephrogenic systemic fibrosis after GBCA exposure and performed an electrophysiologic study of this condition.
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