J Korean Sleep Res Soc.  2013 Dec;10(2):56-58.

A Case of Atypical Kleine-Levin Syndrome

Affiliations
  • 1Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Korea. neuromd@knu.ac.kr
  • 2Brain Science & Engineering Institute, Kyungpook National University, Daegu, Korea.

Abstract

Kleine-Levin syndrome is characterized by recurrent episodes of hypersomnia and associated cognitive and behavioral impairments. We present a 47-year-old female patient with recurrent hypersomnia and disorder of appetite. During each episode, patient slept more than 24 hours with hyperphagia or anorexia. Physical examinations, laboratory tests, and brain MRI showed no significant abnormality in the patient. Nocturnal polysomnographic study showed high sleep efficiency, reduced sleep latency and rapid eye movement (REM) sleep latency, and increased sleep stage 1 & 2. The multiple sleep latency tests showed one episode of sleep-onset REM periods. This is the first atypical case report of Kleine-Levin syndrome in Korea which showed short duration of episodes and hypersomnia combined with anorexia.

Keyword

Kleine-Levin syndrome; Hypersomnia; Anorexia

MeSH Terms

Anorexia
Appetite
Brain
Disorders of Excessive Somnolence
Female
Humans
Hyperphagia
Kleine-Levin Syndrome*
Korea
Magnetic Resonance Imaging
Middle Aged
Physical Examination
Sleep Stages
Sleep, REM
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