J Korean Rheum Assoc.  2006 Mar;13(1):70-75.

A Case of Kaposi's Sarcoma in a Systemic Lupus Erythematosus Patient after Long Term Immune Suppression

Affiliations
  • 1Department of Internal Medicine, Inha University College of Medicine, Incheon, Korea. parkwon@inha.ac.kr
  • 2Department of Pathology, Inha University College of Medicine, Incheon, Korea.

Abstract

A 41-year-old woman was admitted because of dyspnea on exertion for one month. She was diagnosed to have systemic lupus erythematosus 4 years ago and has taken prednisolone and azathioprine. One month prior to admission she visited dental clinic for painful gingival swelling and gingival biopsy was performed. Physical examination showed multiple round elevated purpuric rashes in thoracic wall. Gingiva and skin biopsy showed Kaposi's sarcoma. Computed tomography of abdomen and chest revealed ill-defined nodules in both lung fields and multiple small para-aortic lymphadenopathies. Chemotherapy with paclitaxel was given for Kaposi's sarcoma. Prednisolone was tapered. After the 7th course of chemotherapy, the lesions show marked improvement in size and number.

Keyword

SLE; Kaposi's sarcoma; Immune suppression

MeSH Terms

Abdomen
Adult
Azathioprine
Biopsy
Dental Clinics
Drug Therapy
Dyspnea
Exanthema
Female
Gingiva
Humans
Lung
Lupus Erythematosus, Systemic*
Paclitaxel
Physical Examination
Prednisolone
Sarcoma, Kaposi*
Skin
Thoracic Wall
Thorax
Azathioprine
Paclitaxel
Prednisolone
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