J Korean Rheum Assoc.  2006 Dec;13(4):327-332.

A Case of Intramuscular Abscess Caused by Nocardia farcinica in a Patient with Lupus Nephritis Concurrent with Pulmonary Tuberculosis

Affiliations
  • 1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
  • 2Division of Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University College of Medicine, Seoul, Korea.
  • 3Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, Korea. scbae@hanyang.ac.kr
  • 4Department of Laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea.

Abstract

Nocardiosis is usually a subacute infection, which can occur as an opportunistic infections in patients with systemic lupus erythematosus. There are rare cases of nocardiosis concurrent with Mycobacterium tuberculosis. We report a case of intramuscular nocardial abscess concurrent with pulmonary tuberculosis in a patient with lupus nephritis. She has received cyclophosphamide pulse therapies and is receiving oral steroid therapy 3 months ago. After Nocardia farcinica and Mycobacterium tuberculosis were confirmed by PCR and PCR-RFLP, we initiated trimethoprim/ sulfamethoxazole and antituberculous agents. After then, patient was improved and discharged, maintaining the medications.

Keyword

Systemic lupus erythematosus; Lupus nephritis; Nocardia; Pulmonary tuberculosis

MeSH Terms

Abscess*
Cyclophosphamide
Humans
Lupus Erythematosus, Systemic
Lupus Nephritis*
Mycobacterium tuberculosis
Nocardia Infections
Nocardia*
Opportunistic Infections
Polymerase Chain Reaction
Sulfamethoxazole
Tuberculosis, Pulmonary*
Cyclophosphamide
Sulfamethoxazole
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