J Korean Rheum Assoc.
2010 Jun;17(2):177-182. 10.4078/jkra.2010.17.2.177.
Posterior Reversible Encephalopathy Syndrome in a Patient with Lupus Nephritis
- Affiliations
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- 1Department of Allergy and Rheumatology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea. chsuh@ajou.ac.kr
- KMID: 2201965
- DOI: http://doi.org/10.4078/jkra.2010.17.2.177
Abstract
- Posterior reversible encephalopathy syndrome (PRES) has been described in various clinical settings, including severe hypertension, eclampsia, lupus and immunosuppressive therapy. We report a 27 year-old female systemic lupus erythematosus patient who developed severe headache, seizure and hemiparesis during her lupus nephritis flare. Magnetic resonance image (MRI) showed multi-focal high signal intensity lesions in the parieto-occipital cortex bilaterally and in the subcortical white matter. Her condition improved with immunosuppressive treatments, antihypertensives and hemodialysis. The extent of her lesions decreased on follow-up MRI 2 months later. This case suggests that PRES can be treated with immunosuppressive drugs that do not increase blood pressure.
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