J Korean Pain Soc.  1995 Nov;8(2):266-271.

Comparison of Continuous Epidural Infusion of Narcotic Analgesics and Local Anesthetics Using 2-day Infusor and Meperidine IM. on Postoperative Analgesia

• Kim JS
• Lee KC
• Kang PS
• Lee YC

Abstract

Recently, continuous epidural infusion of narcotics and local anesthetics have been used for postoperative pain relief. This study was designed to compare the analgesic efficacy and side effects of continuous epidural infusion of narcotics and local anesthetics with those of intramuscular administration of meperidine, for postoperative pain relief after cesarean section. Forty patients were divided into 2 groups of 20 patients each.; Continuous epidural group and control (IM meperidine) group. Before each operation, the epidural group had an epidural catheter placed (Ll-2) and following each operation, a bolus of 1%-8 ml of lidocaine was injected, followed by continuous infusion of morphine 3 mg/day, fentanyl 300 g, 2% mepivacaine 20 ml, 0.5% bupivacaine 20 ml and normal saline 40 ml. The control group received meperidine 50 mg IM injection as needed. We evaluated analgesic efficacy with VAS (Visual analogue scale) and side effects at 1, 6, l2, 24, 36 and 48 hour intervals after the operation. The results were as follows: 1) Continuous epidural group was superior to the control group with respect to postoperative analgesia. 2) Side effects (pruritus, nausea & vomiting) were more frequent in the epidural group.

Keyword

Postoperative analgesia; Continuous epidural infusion; Morphine; Fentanyl; Mepivacaine; Bupivacaine; Meperidine

MeSH Terms

Analgesia*
Anesthetics, Local*
Bupivacaine
Catheters
Cesarean Section
Female
Fentanyl
Humans
Infusion Pumps*
Lidocaine
Meperidine*
Mepivacaine
Morphine
Narcotics*
Nausea
Pain, Postoperative
Pregnancy
Anesthetics, Local
Bupivacaine
Fentanyl
Lidocaine
Meperidine
Mepivacaine
Morphine
Narcotics