J Korean Soc Endocrinol.
2003 Feb;18(1):79-84.
A Case of Acute Rhabdomyolysis as a first Manifestation of Primary Hypothyroidism
- Affiliations
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- 1Department of Internal Medicine, Ujongbu St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Abstract
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Various symptoms, such as bradycardia, hypotension, fatigue, constipation, myalgia, muscle weakness, delayed tendon reflex, and so forth, presented in hypothyroidism. Of these symptoms, muscle weakness, myalgia, and delayed tendon reflex are common features of hypothyroid myopathy. Acute rhabdomyolysis, a very severe form of myopathy, but is a rare manifestation of primary hypothyrodism. A 29-year-old man developed acute rhabdomyolysis, associated with primary hypothyroidism as a first manifestation. After thyroxine replacement therapy, he exhibited some improvement in muscle weakness and in non-pitting edema. We report a case of primary hypothyroidism presenting with spontaneous rhabdomyolysis as a first manifestation.