J Lung Cancer.  2008 Dec;7(2):90-92. 10.6058/jlc.2008.7.2.90.

Pilomatrix Carcinoma with Lung and Lymph Node

• Kim KU
• Lee MK
• Kim YS
• Park HK
• Lee CH
• Kim YD
• Jeong YJ
• Park SK

• KMID: 2200033
• DOI: http://doi.org/10.6058/jlc.2008.7.2.90

Abstract

Metastases Pilomatrix carcinoma is a rare locally aggressive hair-follicle tumor. We report a 54-year-old man who presented with a tumor in the left flank that was found by skin biopsy to be pilomatrix carcinoma. A contrast-enhanced computed tomographic scan of the chest, abdomen, and pelvis showed multiple small nodules in both lungs and lymphadenopathy in the abdomen. Video-assisted thoracoscopic biopsy of the lung lesions was consistent with metastatic pilomatrix carcinoma. After intravenous cisplatin and 5-fluorouracil, the skin, lung, and lymph node lesions shrank

Keyword

Pilomatrix carcinoma; Multiple metastases; Chemotherapy

MeSH Terms

Abdomen
Biopsy
Cisplatin
Fluorouracil
Humans
Lung
Lymph Nodes
Lymphatic Diseases
Middle Aged
Neoplasm Metastasis
Pelvis
Skin
Thorax
Cisplatin
Fluorouracil

Figure

• 

  Fig. 1. Initial chest CT scan showing branching opacities with tree-in-bud appearance consistent with tortuous pulmonary arteriolar dilatation by tumor embolism in both lungs.

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  Fig. 2. Lung biopsy showing a nest of basaloid tumor cells with hyperchromatic, pleomorphic nuclei and small distinct nucleoli and necrotic or shadow cells in the center (Hematoxylin-eosin, ×100).

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  Fig. 3. Follow-up chest CT scan after four courses of cisplatin and 5-fluorouracil demonstrating improvement of lung lesions.

Reference

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