J Korean Radiol Soc.  1989 Dec;25(6):917-922. 10.3348/jkrs.1989.25.6.917.

CT findings of mediastinal lymph node metastasis in bronchogenic carcinoma of the lung: A comparative study of small cell carcinoma vs non-small cell carcinoma

• Kwak BK
• Park MS
• Song KS
• Lee KS
• Kim KS

• KMID: 2359025
• DOI: http://doi.org/10.3348/jkrs.1989.25.6.917

Abstract

Small cell carcinoma of the lung is different from non-small cell carcinoma of the lung in many respects such as its tendency toward earlier distant metastasis and principles of treatment. Although radiological findings of small cell carcinoma of the lung are well known including CT and many articles are published about the bronchogenic carcinoma of the lung. Many of them are reports on the staging of bronchogenic carcinoma and criteriaof mediastinal lymph node metastasis by its size. None of them deals with the possibilities of differentiating small cell carcinoma and non-small cell carcinoma of the lung by the morphologic characteristics of metastasized mediastinal lymph nodes. We analyzed retrospectively CT scans of 31 patients with pathologically proven bronchogenic carcinoma of the lung who had mediastinal lymph node metastasis with special attention to the possibilities of differentiating small cell carcinoma from non-small cell carcinoma by the morphologic characteristics of lymph nodeds. 11 of the 31 paitents were small cell carcinoma of the lung and 20 patients werenon-small cell carcinoma including 17 cases of squamous cell carcinoma, 1 case of adenocarcinoma, large cell undifferentiated carcinoma and bronchioloalveolar cell carcinoma respectively. Mediastinal lymph nodes in small cell carcinomas tends to be larger in size (over 2cm in two-thirds of patients) than non-small cell carcinoma. Mean number of the involved lymph nodes in small cell carcinoma are twice as many as that non-small cellcarcinoma. High incidence of central low density of involved lymph node was found in both small cellcarcinoma(80.5%) and non-small cell carcinoma (77.5%) but homogeneous central low density is more frequent insmall cell carcinoma(50%) than non-small cell carcinoma(23.6%). High incidence of peripheral rim enhancement ofinvolved lymph nodes was found both in small cell carcinoma(79.0%) and non-small cell carcinoma(87.3%). There wasno difference between small cell carcinoma and non-small cell carcinoma in respect to involved nodal groups.

MeSH Terms

Adenocarcinoma
Carcinoma
Carcinoma, Bronchogenic*
Carcinoma, Small Cell*
Carcinoma, Squamous Cell
Humans
Incidence
Lung*
Lymph Nodes*
Neoplasm Metastasis*
Retrospective Studies
Tomography, X-Ray Computed