J Korean Radiol Soc.
1995 Apr;32(4):579-586.
CT and MR Imaging in Staging Non-Small Cell Bronchogenic Carcinoma
Abstract
- PURPOSE
To evaluate accuracy of magnetic resonance(MR) imaging for staging of lung cancer and to
compare the accuracies of CT and MRI.
MATERIALS AND METHODS
We retrospectively analyzed 25 cases of lung cancer, which were confirmed
surgically and pathologically. Five experienced radiologists participated in the receiver operating characteristic
(ROC) analysis to evaluate and compare accuracies of the CT and MR imaging in preoperative staging of non
small cell lung cancer by assessing tumor invasion of bronchus, mediastinum, chest wall, and hilar or
mediastinal lymph node metastasis. Imaging results were evaluated against "truth" data based on both surgery and
pathologic examination.
RESULTS
Sensitivity of CT in distinguishing T3-T4 tumors was 60% ;specificity was 76%. These values for MR
imaging were not significantly different(53% and 72%). With ROC analysis, no difference existed between
accuracies of CT and MR imaging in diagnosis of bronchial involvement, but MR imaging was significantly
more accurate than CT(p<0.05) in diagnosis of mediastinal invasion. There was no significant difference
between accuracies of CT and MR imaging in detecting mediastinal node metastasis(N2 or N3); sensitivities were
64% and 78%, respectively, and specificities were 64% and 66%.
CONCLUSION
There was no significant difference in accuracies of CT and MR imaging in preoperative tumor
classification and assessment of mediastinal node metastasis, but MR imaging was more accurate than CT in
assessment of mediastinal invasion.