Korean J Med.
2005 Feb;68(2):229-232.
A case of pilomatrix carcinoma with lung metastasis
- Affiliations
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- 1Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea. hemon@pusan.ac.kr
Abstract
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Pilomatrix carcinoma, the malignant counterpart of pilomatrixoma, is very rare. The tumor is locally aggressive with a great tendency for recurrence, but the metastatic potential is limited. Here we present a case report of pilomatrix carcinoma from left flank region with lung and lymph node metastasisn in 53-year-old male. Histologically, it has nuclear pleomorphism and blood vessel infiltration in contrast to pilomatrixoma. Both skin and lung lesions have been improved by 6 cycles of systemic chemotherapy with cisplatin and 5-fluorouracil.