J Korean Soc Endocrinol.  2000 Oct;15(4-5):591-594.

A Case of Synchronized Pineal and Suprasellar Germinoma

Affiliations
  • 1Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.

Abstract

Pineal germinomas are the most common intracranial germ cell tumor and occur in relatively young age, with 26% between 10 and 12, 65% between 10 and 21 and 95% before age 27. Patients with pineal germinoma present headache, lethargy, nausea, and vomiting which result from raised intracranial pressure and Parinaud's syndrome secondary to midbrain tectal compression, and rarely endocrine dysfunction such as diabetes insipidus (DI), panhypopituitarism, and precocious puberty. We experienced a case of pineal and suprasellar germinoma presenting with central diabetes insipidus and panhypopituitarism.


MeSH Terms

Diabetes Insipidus
Diabetes Insipidus, Neurogenic
Germinoma*
Headache
Humans
Intracranial Pressure
Lethargy
Mesencephalon
Nausea
Neoplasms, Germ Cell and Embryonal
Ocular Motility Disorders
Puberty, Precocious
Vomiting
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