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A Cortical Substrate for Square-Wave Jerks in Progressive Supranuclear Palsy

Anagnostou E, Karavasilis E, Potiri I, Constantinides V, Efstathopoulos E, Kapaki E, Potagas C

BACKGROUND AND PURPOSE: Square-wave jerks (SWJs) are the most common saccadic intrusion in progressive supranuclear palsy (PSP), but their genesis is uncertain. We aimed to determine the characteristics of SWJs...
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Increased Signal in the Superior Cerebellar Peduncle of Patients with Progressive Supranuclear Palsy

Kataoka H, Nishimori , Kiriyama T, Nanaura H, Izumi T, Eura N, Iwasa N, Sugie K

OBJECTIVE: The provisional diagnosis of progressive supranuclear palsy (PSP) depends on a combination of typical clinical features and specific MRI findings, such as atrophy of the tegmentum in the midbrain....
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Promising Neuroimaging Biomarkers in Depression

Lai CH

The neuroimaging has been applied in the study of pathophysiology in major depressive disorder (MDD). In this review article, several kinds of methodologies of neuroimaging would be discussed to summarize...
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A case of Wernicke's encephalopathy following complicated laparoscopic pylorus-preserving pancreaticoduodenectomy

Kim JS, Rho SY, Hwang HK, Lee WJ, Kang CM

Laparoscopic pylorus-preserving pancreaticoduodenectomy (PPPD)/pancreaticoduodenectomy (PD) is cautiously regarded as a safe and effective approach in well-selected patients with periampullary cancer. However, postoperative pancreatic fistula (POPF), delayed gastric emptying (DGE), postoperative...
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Parkinson's Disease: The Emerging Role of Gut Dysbiosis, Antibiotics, Probiotics, and Fecal Microbiota Transplantation

Dutta SK, Verma S, Jain V, Surapaneni BK, Vinayek R, Phillips L, Nair PP

  • KMID: 2454635
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):363-376.
  • doi: 10.5056/jnm19044
The role of the microbiome in health and human disease has emerged at the forefront of medicine in the 21st century. Over the last 2 decades evidence has emerged to...
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Ramsay Hunt Syndrome Complicated by Meningoencephalitis and Radiologic findings: a Rare Case Report

Lee Y, Lee D

Ramsay Hunt syndrome with the complication of encephalitis or meningoencephalitis is rarely reported and uncommon in immunocompetent patients. The radiological manifestations of such cases usually involve the cerebellum and brainstem...
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GABAergic neuronal development in the embryonic mesencephalon of mice

This study presents neurogenesis and neuronal migration patterns of gamma-aminobutyric acid-ergic (GABAergic) neurons during mesencephalic development of mouse. After neurons from embryonic day (E) 10-16 were labelled by a single...
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Three-Dimensional Analysis of Mouse Habenula Subnuclei Reveals Reduced Volume and Gene Expression in the Lipopolysaccharide-mediated Depression Model

Yang E, Kim JY, Yang SH, Lee E, Sun W, Lee HW, Kim H

The habenula (Hb) is small but important brain structure, anatomically and functionally links the forebrain with the midbrain to modulate various neuropsychiatric functions associated with drug addiction and emotion-associated dysfunctions....
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Combination of In Vivo [¹²³I]FP-CIT SPECT and Microdialysis Reveals an Antipsychotic Drug Haloperidol-induced Synaptic Dopamine Availability in the Rat Midbrain and Striatum

Park SH, Song YS, Moon BS, Lee BC, Park HS, Kim SE

Synaptic dopamine (DA) is mainly regulated by the presynaptic DA transporter (DAT). Single-photon emission computerized tomography (SPECT) with the DAT radiotracer [¹²³I]FP-CIT assesses changes in synaptic DA availability when endogenous...
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Clinical Factors Associated with Videofluoroscopic Swallowing Study Findings in Stroke Patients

Lee JM, Kim J, Han SH, Park JH, Kim JH

OBJECTIVE: To examine the clinical factors and brain lesion locations related to the patterns of dysphagia in stroke patients in a rehabilitation hospital. METHODS: The medical records of 116 stroke patients...
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Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2

Kim M, de la Peña JB, Cheong JH, Kim HJ

Most organisms have adapted to a circadian rhythm that follows a roughly 24-hour cycle, which is modulated by both internal (clock-related genes) and external (environment) factors. In such organisms, the...
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A case of acute bilateral thalamic infarction presenting in a sleep-like coma after alcohol ingestion

Kim JE, Park SY, Jeong JW, Lee JH, Kwon IH, Choi Y

The artery of Percheron is a rare anatomical variant, in which a common trunk arises from one posterior cerebral artery and then branches to supply each of the thalami and...
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Metronidazole-Induced Encephalopathy with Thiamine Deficiency

Kim RY, Lee DS, Gwag BC, Lee YK, Cheon SM, Jeong JH

Metronidazole-induced encephalopathy (MIE) can be caused by excessive dose or prolonged metronidazole administration. The signal abnormalities in the cerebellar dentate nuclei, midbrain, dorsal pons and corpus callosum on magnetic resonance...
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Bilateral Vertical Gaze Palsy after Cerebral Digital Subtraction Angiography Due to Unilateral Midbrain Infarction

Kim JH, Kim WJ

No abstract available.
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Leigh Syndrome: Subgroup Aanalysis according to Mitochondrial DNA Mutation

Jee NL, Her SM, Kim SH, Lee MJ, Lee CH, Lee YM

PURPOSE: Leigh syndrome (LS) is a rare, progressive neurodegenerative disorder with characteristic abnormalities in the central nervous system. Such patients present with heterogeneous clinical symptoms and genetic abnormalities; thus, prognosis...
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Magnetic Resonance Image Texture Analysis of the Periaqueductal Gray Matter in Episodic Migraine Patients without T2-Visible Lesions

Chen Z, Chen X, Liu M, Liu S, Yu S, Ma L

OBJECTIVE: The periaqueductal gray matter (PAG), a small midbrain structure, presents dysfunction in migraine. However, the precise neurological mechanism is still not well understood. Herein, the aim of this study...
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Neurogenesis and neuronal migration of dopaminergic neurons during mesencephalon development in mice

Kim MK, Lee SJ, Vasudevan , Won C

Dopaminergic neurons are one of the major neuronal components in the brain. Mesencephalon dopamine (DA) neurogenesis takes place in the ventricular zone of the floor plate, when DA progenitors divide...
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Regional difference in spontaneous firing inhibition by GABA(A) and GABA(B) receptors in nigral dopamine neurons

Kim Y, Jang J, Kim HJ, Park MK

GABAergic control over dopamine (DA) neurons in the substantia nigra is crucial for determining firing rates and patterns. Although GABA activates both GABA(A) and GABA(B) receptors distributed throughout the somatodendritic...
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Trochlear Nerve Palsy Caused by Quadrigeminal Cistern Lipoma

Choi NH, Kim WJ, Kim MM

PURPOSE: To report a case of trochlear nerve palsy caused by quadrigeminal cistern lipoma located in the dorsal midbrain. CASE SUMMARY: A 65-year-old male visited our clinic for intermittent vertical diplopia...
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Tau Positron Emission Tomography Imaging in Degenerative Parkinsonisms

Lyoo CH, Cho H, Choi JY, Ryu YH, Lee MS

In recent years, several radiotracers that selectively bind to pathological tau proteins have been developed. Evidence is emerging that binding patterns of in vivo tau positron emission tomography (PET) studies...
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