J Korean Soc Ther Radiol Oncol.  2005 Jun;23(2):111-115.

Malignant Melanoma of the Vagina: A Report of 2 Cases

Affiliations
  • 1Departments of Radiation Oncology, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea. obkim500@dsmc.or.kr
  • 2Departments of Gynecology, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea.
  • 3Departments of Bio-physics Medical Engineering, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea.

Abstract

Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly in postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of loco- regional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor in spite of such a radical approache. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have promising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy.

Keyword

Malignant melanoma; Vagina; Radiation therapy

MeSH Terms

Female
Humans
Melanoma*
Prognosis
Radiotherapy
Recurrence
Vagina*
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