J Korean Soc Ther Radiol Oncol.
2005 Jun;23(2):111-115.
Malignant Melanoma of the Vagina: A Report of 2 Cases
- Affiliations
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- 1Departments of Radiation Oncology, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea. obkim500@dsmc.or.kr
- 2Departments of Gynecology, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea.
- 3Departments of Bio-physics Medical Engineering, Dongsan Medical Center, School of Medicine, Keimyung University, Daegu, Korea.
Abstract
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Primary malignant melanoma of the vagina is an extremely rare genital neoplasm occurring mainly in postmenopausal women. It has a worse prognosis than cutaneous melanomas, because of the high rate of loco- regional recurrences and rapid systemic dissemination. In the past, radical surgical extirpation as the primary management had been recommended to improve loco-regional control, and possibly overall survival. However, the prognosis was poor in spite of such a radical approache. Recently, more conservative treatment such as wide local excision combined with adjuvant high-dose fraction radiotherapy seems to have promising results. Primary radiation therapy could be served as an alternative to surgery for patients with lesion less than 3 cm in diameter. We report 2 cases of primary vaginal malignant melanoma treated with radiotherapy.