J Korean Soc Ther Radiol.  1988 Dec;6(2):253-258.

The Radiation Effect on Peripheral Blood Cell

• Lee TJ
• Kwon HC
• Kim JS
• Im SK
• Choi KC

Abstract

To evaluate radiation effect on the hematopoietic system, we analyzed 44 patients who were treated with conventionally fractionated radiation therapy (RT) at Chonbuk National University Hospital. According to the treatment sites, we classified them into three groups: group I as head and neck, group II as thorax, and group III as pelvis. White blood cell, lymphocyte, platelet and hemoglobin were checked before and during RT The results were as follow; 1. White blood cell (WBC) and lymphocyte count were declined from the first week of RT to the third week, and then slightly recovered after the third or fourth week. There was prominent decrease in lymphocyte counts than WBC. 2. Platelet counts were declined until the second week of the RT, showed slight recovery at fourth week in all groups. Hemoglobin values were slightly decreased in the first week and then recovered the level of pretreatment value, gradually. 3. Lymphocyte count were declined significantly on group III(p<0.01), WBC and platelet counts were decreased on group II but statistically not significant.

Keyword

Hematopoietic system; Radiation Therapy

MeSH Terms

Blood Cells*
Blood Platelets
Head
Hematopoietic System
Humans
Jeollabuk-do
Leukocytes
Lymphocyte Count
Lymphocytes
Neck
Pelvis
Platelet Count
Radiation Effects*
Thorax