Korean J Pediatr.  2008 Feb;51(2):214-218. 10.3345/kjp.2008.51.2.214.

Palliative effect of (131)I-MIBG in relapsed neuroblastoma after autologous peripheral blood stem cell transplantation

Affiliations
  • 1Department of Hematology/Oncology, Yeungnam University College of Medicine, Korea. johah@med.yu.ac.kr

Abstract

Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine ((131)I-MIBG) therapy is an alternative approach to treat stage IV neuroblastoma. We report the palliative effect of (131)I-MIBG in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. (131)I-MIBG is an effective and relatively nontoxic palliative therapy resulting in reduction of pain and prolongation of survival.

Keyword

Relapsed neuroblastoma; (131)I-MIBG; Palliative therapy

MeSH Terms

Neuroblastoma
Palliative Care
Peripheral Blood Stem Cell Transplantation
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