J Korean Soc Pediatr Endocrinol.  1998 Nov;3(2):250-255.

A Case of Sublingual Thyroid Combined with Pituitary Hyperplasia

• Lee HM
• Shin CH
• Son DW
• Kim KY
• Kim DH
• Park KH
• Choi YS

Abstract

We present a 23months old male patient of pituitary hyperplasia due to sublingual thyroid induced primary hypothyroidism with subsequent return to normal size after thyroxine therapy. Before the levothyroxine treatment, MRI revealed enlargement of the pituitary gland with suprasellar extension. During treatment with levothyroxine, serum T3, T4, and TSH were normal and growth retardation was improved. One year later, repeated MRI showed a decrease in pituitary mass size, with no suprasellar extension. The reversible pituitary mass resolved after treatment with levothyroxine must be considered in patients with pituitary and suprasellar masses.

Keyword

Primary hypothyroidism; Pituitary hyperplasia; Ecpotic thyroid; MRI

MeSH Terms

Humans
Hyperplasia*
Hypothyroidism
Magnetic Resonance Imaging
Male
Pituitary Gland
Thyroid Gland*
Thyroxine
Thyroxine