J Korean Soc Pediatr Endocrinol.  2011 Dec;16(3):185-188. 10.6065/jkspe.2011.16.3.185.

Pituitary Hyperplasia Secondary to Hypothyroidism Caused by Hashimoto's Thyroiditis in a Female Adolescent

Affiliations
  • 1Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea. leedy@jbnu.ac.kr
  • 2Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea.
  • 3Department of Radiology, Chonbuk National University Medical School, Jeonju, Korea.

Abstract

The authors report a case of a 16-year-old girl with pituitary hyperplasia and primary hypothyroidism caused by Hashimoto's thyroiditis. She presented with growth arrest, and hormonal studies showed decreased level of free thyroxine (T4), and increased levels of thyroid-stimulating hormone (TSH) and prolactin. A pituitary magnetic resonance imaging (MRI) showed a suprasellar mass. After 2 months of thyroxine replacement, thyroid function and high prolactin levels normalized, and the pituitary hyperplasia disappeared. This case represents relatively rapid normalization of pituitary hyperplasia, compare to the previous studies.

Keyword

Pituitary gland; Hyperplasia; Hypothyroidism

MeSH Terms

Adolescent
Female
Humans
Hyperplasia
Hypothyroidism
Magnetic Resonance Imaging
Pituitary Gland
Prolactin
Thyroid Gland
Thyroiditis
Thyrotropin
Thyroxine
Prolactin
Thyrotropin
Thyroxine
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