J Korean Neurosurg Soc.  2013 Sep;54(3):250-252. 10.3340/jkns.2013.54.3.250.

Incidental Superior Hypophygeal Artery Aneurysm Embedded within Pituitary Adenoma

Affiliations
  • 1Department of Neurosurgery, Yeungnam University College of Medicine, Daegu, Korea. olkim@med.yu.ac.kr

Abstract

Intra-cranial aneurysm can be incidental findings in patients with pituitary adenomas, and are usually located outside the pituitary region. However, the coexistence of intrasellar (not intracranial) aneurysms with pituitary adenomas is extremely rare. We report a patient with an incidental superior hypophygeal aneurysm embedded within a non-functional pituitary adenoma which was treated by transsphenoidal surgery after endovascular coil embolization.

Keyword

Pituitary adenoma; Aneurysm; Therapeutic embolization; Surgical procedure

MeSH Terms

Aneurysm*
Arteries*
Embolization, Therapeutic
Humans
Incidental Findings
Pituitary Neoplasms*

Figure

  • Fig. 1 Contrast-enhanced T1-wighted magnetic resonance images in the axial (A) and coronal planes (B) demonstrate the aneurysm (arrow) embedded in the pituitary adenoma, located inside the sella turcica and medial to the right internal carotid artery (ICA). Three-dimensional computed tomography angiogram images (C) demonstrate a saccular aneurysm in the opthalmic segment of the right distal ICA (arrow). Four-vessels angiogram (D) demonstrates a right superior hypophyseal aneurysm (arrow).

  • Fig. 2 Four-vessels angiogram after embolization demonstrates the aneurysm that was densely packed with coils (arrow). Anteroposterior view (A), lateral view (B) and three-dimensional view (C).

  • Fig. 3 Contrast-enhanced T1-wighted magnetic resonance (MR) image coronal (A) axial coronal planes (B) at 8 months after transsphenoidal surgery. The MR images demonstrate complete obliteration of the aneurysm and there was no sign of regrowth of the adenoma.


Reference

1. Acqui M, Ferrante L, Matronardi L, d'Addetta R. Alteration of the collagen type III/type I ratio and intracranial saccular aneurysms in GH-secreting hypophyseal adenomas. Ital J Neurol Sci. 1988; 9:365–368. PMID: 3220712.
Article
2. Bulsara KR, Karavadia SS, Powers CJ, Paullus WC. Association between pituitary adenomas and intracranial aneurysms : an illustrative case and review of the literature. Neurol India. 2007; 55:410–412. PMID: 18040122.
Article
3. Fujiwara S, Fujii K, Nishio S, Fukui M. Diagnosis and treatment of pituitary adenoma with adjacent carotid artery aneurysm. J Neurosurg Sci. 1991; 35:41–46. PMID: 1890460.
4. Hanak BW, Zada G, Nayar VV, Thiex R, Du R, Day AL, et al. Cerebral aneurysms with intrasellar extension : a systematic review of clinical, anatomical, and treatment characteristics. J Neurosurg. 2012; 116:164–178. PMID: 22054212.
Article
5. Handa J, Matsuda I, Handa H. Association of brain tumor and intracranial aneurysms. Surg Neurol. 1976; 6:25–29. PMID: 951636.
6. Housepian EM, Pool JL. A systematic analysis of intracranial aneurysms from the autopsy file of the Presbyterian Hospital, 1914 to 1956. J Neuropathol Exp Neurol. 1958; 17:409–423. PMID: 13564252.
Article
7. Jakubowski J, Kendall B. Coincidental aneurysms with tumours of pituitary origin. J Neurol Neurosurg Psychiatry. 1978; 41:972–979. PMID: 712374.
Article
8. Manara R, Maffei P, Citton V, Rizzati S, Bommarito G, Ermani M, et al. Increased rate of intracranial saccular aneurysms in acromegaly : an MR angiography study and review of the literature. J Clin Endocrinol Metab. 2011; 96:1292–1300. PMID: 21307138.
Article
9. Oh MC, Kim EH, Kim SH. Coexistence of intracranial aneurysm in 800 patients with surgically confirmed pituitary adenoma. J Neurosurg. 2012; 116:942–947. PMID: 22304451.
Article
10. Olsen WL, Brant-Zawadzki M, Hodes J, Norman D, Newton TH. Giant intracranial aneurysms : MR imaging. Radiology. 1987; 163:431–435. PMID: 3562822.
11. Pant B, Arita K, Kurisu K, Tominaga A, Eguchi K, Uozumi T. Incidence of intracranial aneurysm associated with pituitary adenoma. Neurosurg Rev. 1997; 20:13–17. PMID: 9085282.
Article
12. Sade B, Mohr G, Tampieri D, Rizzo A. Intrasellar aneurysm and a growth hormone-secreting pituitary macroadenoma. Case report. J Neurosurg. 2004; 100:557–559. PMID: 15035295.
Article
13. Sasagawa Y, Tachibana O, Shiraga S, Takata H, Akai T, Iizuka H. [A clinical feature and therapeutic strategy in pituitary adenomas associated with intracranial aneurysms]. No Shinkei Geka. 2012; 40:15–21. PMID: 22223518.
14. Seda L Jr, Cukiert A, Nogueira KC, Huayllas MK, Liberman B. Intrasellar internal carotid aneurysm coexisting with GH-secreting pituitary adenoma in an acromegalic patient. Arq Neuropsiquiatr. 2008; 66:99–100. PMID: 18392428.
15. Teng MM, Nasir Qadri SM, Luo CB, Lirng JF, Chen SS, Chang CY. MR imaging of giant intracranial aneurysm. J Clin Neurosci. 2003; 10:460–464. PMID: 12852886.
Article
16. Torres A, Dammers R, Krisht AF. Bilateral internal carotid artery aneurysm simulating pituitary apoplexy : case report. Neurosurgery. 2009; 65:E1202. discussion E1202. PMID: 19934939.
17. Wakai S, Fukushima T, Furihata T, Sano K. Association of cerebral aneurysm with pituitary adenoma. Surg Neurol. 1979; 12:503–507. PMID: 524269.
18. Yang MY, Chen C, Shen CC. Cavernous aneurysm and pituitary adenoma : management of dual intrasellar lesions. J Clin Neurosci. 2005; 12:477–481. PMID: 15925789.
Article
19. Yu K, Herwadkar A, Kearney T, Gnanalingham KK. Pituitary adenoma and incidental superior hypophyseal aneurysm. Br J Neurosurg. 2011; 25:432–433. PMID: 20854061.
Article
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