J Korean Soc Osteoporos.
2010 Apr;8(1):82-87.
Low Bone Mass Related with Helicobacter pylori Infection in a Woman
- Affiliations
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- 1Department of Family Medicine, Kosin University, College of Medicine, Busan, Korea.
- 2Department of Obstetrics & Gynecology, Kosin University, College of Medicine, Busan, Korea.
- 3Department of Obstetrics & Gynecology, Konkuk University Medical Center, Seoul, Korea.
- 4Department of Family Medicine, Cheil General Hospital & Women's Healthcare Center, Seoul, Korea.
- 5Department of Obstetrics & Gynecology, Kyung Hee University Medical Center, Seoul, Korea.
- 6Department of Obstetrics & Gynecology, Inje University Sanggyepaik Hospital, Seoul, Korea. hchoi@sanggyepaik.ac.kr
Abstract
- A 39-year-old female had intermittent dyspepsia for 1 year. She was not a current smoker or an alcohol abuser. An upper gastrointestinal endoscopy showed erosive gastritis; the histologic diagnosis of the gastric mucosa was active gastritis with Helicobacter pylori infection. Dual-energy X-ray absorptiometry confirmed marked osteopenia at Wards' region of the left femur; the bone mineral density was 0.605 g/cm2 and the Z-score was -1.8 (69%). The serum C-telopeptide was 0.259 ng/mL and the serum osteocalcin was 10.24 ng/mL. There were no significant muscle weakness, tenderness, or no joint abnormalities. It is required to consider as a secondary cause of osteopenia in patients with H. pylori infection in stomach and is essential to measure bone mineral density.
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