J Korean Geriatr Soc.  2001 Jun;5(2):196-199.

A Reversible Posterior Leukoencephalopathy Syndrome

• Kim DS
• Kim YD
• Choi YC

Abstract

Reversible posterior leukonecephalopathy syndrome RPLS), a neurologie disorder associated with evidence of posterior cerebral edema on neuroimaging studies, has been described in both adults and children. Conditions predisposing to RPLS include malignant hypertension, renal dysfunction, toxemia of pregnancy, interferon therapy, and the use of immunosuppressive agents. When associated with acute hypertension, RPLS typically occurs concurrently with the fulminant clinical syndrome of hypertensive encephalopathy We describe occipital lobe seizures, in the setting of only moderate elevations of blood pressure, as the major clinical manifestation of RPLS.

Keyword

Reversible posterior leukoencephaiopathy; Hypertensive encephlaopathy; Occipital lobe seizure

MeSH Terms

Adult
Blood Pressure
Brain Edema
Child
Humans
Hypertension
Hypertension, Malignant
Hypertensive Encephalopathy
Immunosuppressive Agents
Interferons
Neuroimaging
Occipital Lobe
Posterior Leukoencephalopathy Syndrome*
Pre-Eclampsia
Seizures
Immunosuppressive Agents
Interferons