J Korean Soc Neonatol.  2011 May;18(1):158-163. 10.5385/jksn.2011.18.1.158.

Two Cases of Dry Lung Syndrome

Affiliations
  • 1Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. kimhans@snu.ac.kr

Abstract

Preterm infants with oligohydramnios after preterm premature rupture of membranes can present with severe respiratory distress immediately after birth, and the most common cause is pulmonary hypoplasia. Unlike infants with pulmonary hypoplasia, some cases have shown dramatic improvement with aggressive ventilatory support during the initial 1-2 days of distress; those patients have been defined as having dry lung syndrome. It is assumed that oligohydramnios leads to functional pulmonary hypoplasia by compression of the fetal lungs; some of the improvement in dry lung syndrome may thus have resulted from inflation of compressed lung tissue and increase of lung compliance. We report two incidences of dry lung syndrome that were treated successfully with high inflation pressure and inhaled nitric oxide (NO); these are the first dry lung syndrome cases to be reported in Korean infants.

Keyword

Preterm birth; Respiratory distress syndrome of newborn; Pulmonary hypoplasia

MeSH Terms

Female
Humans
Incidence
Infant
Infant, Newborn
Infant, Premature
Inflation, Economic
Lung
Lung Compliance
Membranes
Nitric Oxide
Oligohydramnios
Parturition
Pregnancy
Premature Birth
Rupture
Nitric Oxide
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