J Korean Neurol Assoc.  2005 Aug;23(4):557-560.

A Case of Cryptococcal Meningitis with Bilateral Internuclear Ophthalmoplegia and Ptosis

Affiliations
  • 1Department of Neurology, Gyeongsang National University College of Medicine, Jinju, Korea. oykwon@nongae.gsnu.ac.kr
  • 2Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.

Abstract

A 73-year-old woman with long-term steroid medication for arthralgia, suffered a sudden decrement of mental status, bilateral internuclear ophthalmoplegia and ptosis. T2-weighted MR images revealed high signals in the midbrain and both thalami. In cerebrospinal fluid studies, a test for cryptococcal antigen was positive and Cryptococcus neoformans was cultured. Bilateral internuclear ophthalmoplegia and ptosis may develop in cryptococcal meningitis from ischemic complications.

Keyword

Cryptococcal meningitis; Internuclear ophthalmoplegia

MeSH Terms

Aged
Arthralgia
Cerebrospinal Fluid
Cryptococcus neoformans
Female
Humans
Meningitis, Cryptococcal*
Mesencephalon
Ocular Motility Disorders*
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