J Korean Neurol Assoc.
1989 Jun;7(1):89-94.
A Case of Podophyllin Induced Peripheral Neuropathy
- Affiliations
-
- 1Department of Neurology, College of Medicine, Seoul National University.
- 2Department of Pathology, College of Medicine, Seoul National University.
Abstract
- Podophyllin is known as a neurotoxin, We recently observed a 34-year-old woman with podophyllin induced peripheral neuropathy. She was treated with topical podophyllin for perianal multiple condyloma acuminata. One day after application, she complained of G-I symptoms ( abdominal pain, nausea, vomiting, diarrhea), followed by tingling sensation on all extremities. We confirmed peripheral neuropathy with electrophysiologic study and sural nerve biopsy. She has improved on follow-up.
