J Korean Assoc Maxillofac Plast Reconstr Surg.
1998 Aug;20(3):217-227.
An experimental study on the effect of calcium sulfate on bone regeneration
- Affiliations
-
- 1Department of OMFS, Medical Research Center, College of Medicine, Ehwa Womans University.
Abstract
- Calcium sulfate(plaster of Paris) has been used in dental and orthopedic surgery for about 100 years. It is well known that the plaster is bioresorbable, biocompatible, defect conformable and moldable. The purpose of this study is to evaluate two effects of calcium sulfate on bone regeneration, that is, the effects of graft materials and barrier for bone regeneration. Cortical bone defects were formed for recipient site on the femurs of 19 Sprague-Dawley rats. The autogenous particulated bone and calcium sulfate were grafted to the defects. Calcium sulfate paste, Gore-TexR membrane(W.L. GORE & ASSOCIATES LTD., U.S.A.) and rubber sheet were used for the shielding materials. The results were as follows: 1. Calcium sulfate that had been grafted in the cortical bone defect was almost resorbed before bone remodeling, resultantly had little effect on bone regeneration. 2. Resoption process of calcium sulfate grafted on the bone grafting area tends to be accelerated, as being divided into numerous small particles progressively. Under the situation where the calcium sulfate was protected, with the coverage of fascia, Gore-TexR membrane or rubber sheet, new bone formation was confirmed with presence of calcium sulfate particles over 6 weeks after grafting. 3. In the case of calcium sulfate covered with membrane, distinct bone formation was observed on the marrow space of femur adjacent to the plaster mass. 4. Rubber shielded plaster group revealed new bone trabeculae under the rubber sheet, but it showed ischemic degeneration of superficial cortical bone.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Periodontal repair in dogs: effect of the modified calcium sulfate paste on the 1-wall intrabony defects
- The Effect of composite Graft of allogenic DFDB and Calcium Sulfate with and without Calcium Sulfate barrier in Periodontal 1 wall intrabony defects in Dogs
- A Histo-Pathological Study of Effect on Periodontal Regeneration with Calcium Sulfate Membrane on The Grade II Furcation Defects in Beagle Dogs
- The effects of composit grafts of allogenic decalcified freeze Dried bone and calcium sulfate on the healing of 1-wall intrabony defects in dogs
- The Effect of Calcium Sulfate on the Periodontal Healing of 2-Wall Intrabony Defects in Dogs
