J Korean Assoc Maxillofac Plast Reconstr Surg.  2003 Nov;25(6):509-516.

Evaluation of bone graft materials in the treatment of artificial bone defects around dental implant

• Oh SY
• Kim SG
• Park JC
• Kim JS

Abstract

To evaluate the effects of allografts, xenografts, and bone substitutes on bone formation in peri-implant bone defects, forty Avana implants were inserted into both tibiae of 10 adult rabbits and artificial bone defects (2x2x2 mm) were prepared to the right and left of the implants. The control group received no bone graft, while the defects in the experimental groups were filled with particulate dentin-plaster of Paris (tooth ash), DFDB, or Bio-Oss. The animals were sacrificed 4 or 8 weeks after surgery and specimens were observed by light microscopy. The results were as follows. New immature bone was observed at 4 weeks in the control group, and this new bone was mature lamellar bone at 8 weeks. New immature bone was observed at 4 weeks in the tooth ash group, and similar new immature bone showing good osseointegration was seen at 8 weeks. Active new bone formation was observed at 4 weeks in the DFDB and Bio-Oss groups and mature new bone that was indistinguishable from the adjacent normal bone was seen at 8 weeks. These results indicate that bone graft material accelerates new bone formation, bone maturation, and osseointegration.

Keyword

Particulate dentin-plaster of Paris; DFDB; Bio-Oss

MeSH Terms

Adult
Allografts
Animals
Bone Substitutes
Dental Implants*
Heterografts
Humans
Microscopy
Osseointegration
Osteogenesis
Rabbits
Tibia
Tooth
Transplants*
Bone Substitutes
Dental Implants