J Korean Acad Periodontol.  2008 Sep;38(3):493-502.

The comparative study: the regenerative effect depends on size of bone graft material in bone loss site around dental implant

• O HK
• Hong KS
• Chung CH
• Yim SB

Abstract

PURPOSE
The purpose of this study is to investigate on the regenerative capacity by using different size of graft materials around bony defect around implant. MATERIAL AND METHODS: Dental implant fixtures(Bio-TIS, Korea) were placed into the tibia of 8 rabbits. After placement of implant, artificial defects were created for each group, and the size of bone graft materials were used according to each designated group. 4 weeks after surgery, 8 rabbits were sacrificed. The histologic and histomorphometrical study were done for comparison of the regenerative capacity using 80-90micrometer and 200~1000micrometer size of grafting materials of OCS-B(R). RESULT: Matured bone formation was significantly increased more in Group E1(80-90micrometer) than in Group E2(200~1000micrometer). Group E1(80-90micrometer) showed more significant augmentation in marginal length of graft material per unit area than Group E2(200~1000micrometer). Group E1(80-90micrometer) showed more interspace in graft material than Group E2(200~1000micrometer). Control group showed no new bone formation around and inside of implanted fixture.
CONCLUSION
Small grafting material size has great influence on bone regeneration.

Keyword

Regenerative capacity; dental implant defect; Bone graft materials

MeSH Terms

Bone Regeneration
Dental Implants
Osteogenesis
Prostheses and Implants
Rabbits
Tibia
Transplants
Dental Implants