J Korean Med Assoc.  2003 Nov;46(11):958-964. 10.5124/jkma.2003.46.11.958.

Pharmacological Therapy in Osteoarthritis

• Song YW

• KMID: 2183128
• DOI: http://doi.org/10.5124/jkma.2003.46.11.958

Abstract

Osteoarthdtis (OA) is a common, chronic, and painful disorder characterized by cartilage loss. It is the most common among all rheumatic disorders and is a major cause of disability. OA can be managed with a variety of pharmacological therapies, including acetaminophen, traditional nonsteroidal antiinflammatory drugs, cyclooxygenase2 inhibitors, intraarticular steroids, viscosupplements, glucosamine, chondroitin sulfate, and capsaicin. In this review, I describe the clinical efficacy and side effects of these pharmaceuticals and review diseasemodifying osteoarthritis drugs (DMOAD), such as glucosamine, diacerein, and avocado/soybean unsaponifiables, of which the clinical efficacy still remains to be determined.

Keyword

Osteoarthritis; Acetaminophen; Nonsteroidal anti-inflammatory drug; Disease modifying osteoarthritis drug

MeSH Terms

Acetaminophen
Capsaicin
Cartilage
Chondroitin Sulfates
Glucosamine
Osteoarthritis*
Steroids
Viscosupplements
Acetaminophen
Capsaicin
Chondroitin Sulfates
Glucosamine
Steroids
Viscosupplements

Figure

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  Figure 1

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