Intest Res.  2013 Apr;11(2):134-136. 10.5217/ir.2013.11.2.134.

A Case of Perforated Gastrointestinal Stromal Tumor in the Jejunum as a Rare Cause of Acute Abdomen

• Kim SY
• Kim JH
• Park DS
• Jang GS
• Hong EY
• An JS
• Kim SY
• Kim HY
• Kim DH
• Park JW
• Baek IH
• Park CK

• KMID: 2174283
• DOI: http://doi.org/10.5217/ir.2013.11.2.134

Abstract

Preoperative diagnosis of Gastrointestinal Stromal Tumors (GISTs) in the small intestine is often delayed until complications such as hemorrhage, bowel obstruction or perforation develop. Such GISTs are usually asymptomatic and tumor perforation is an uncommon clinical presentation. In this report, we review the diagnosis, pathology and treatment of a 32-year-old male with a perforated GIST in the jejunum who presented with symptoms of acute abdomen. Abdominal computed tomography (CT) showed a ruptured huge tumor with inhomogeneous density in the small intestine. The patient underwent a complete tumor excision and jejunal segmental resection. A histopathological examination of the tumor confirmed that it was a GIST. Postoperatively, the patient received medical treatment, using oral Imatinib 400 mg daily for 10 months without any signs of disease recurrence. Prognosis is worse in ruptured GISTs and in these cases, complete surgical resection of the tumor must be followed by adjuvant therapy with Imatinib.

Keyword

Gastrointestinal stromal tumors; Intestinal perforation; Imatinib

MeSH Terms

Abdomen, Acute
Benzamides
Gastrointestinal Stromal Tumors
Hemorrhage
Humans
Imatinib Mesylate
Intestinal Perforation
Intestine, Small
Jejunum
Male
Piperazines
Prognosis
Pyrimidines
Recurrence
Benzamides
Piperazines
Pyrimidines