Clin Psychopharmacol Neurosci.
2016 May;14(2):210-211. 10.9758/cpn.2016.14.2.210.
Risperidone-induced Gingival Bleeding in a Pediatric Case: A Dose-dependent Side Effect
- Affiliations
-
- 1Department of Child and Adolescent Psychiatry, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey. herguners@yahoo.com
- 2Department of Psychiatry, Konya Training and Research Hospital, Konya, Turkey.
- 3Department of Orthodontis, Faculty of Dentistry, Selcuk University, Konya, Turkey.
- KMID: 2170990
- DOI: http://doi.org/10.9758/cpn.2016.14.2.210
Abstract
- There are several case reports on risperidone-related bleeding; however, to our knowledge, there is no report about gingival bleeding associated with risperidone in the literature. We presented a case who experienced gingival bleeding when risperidone dose was increased to 0.5 mg/day, and subsided after decreasing the dose to 0.25 mg/day, suggesting a dose-dependent side-effect. The bleeding side effect of risperidone might be caused by several mechanisms, including 5-hydroxytryptamine 2A receptor antagonism. Although bleeding associated with risperidone is rarely reported, clinicians should be aware of this side effect.
