Clin Pediatr Hematol Oncol.
2010 Oct;17(2):204-208.
An Adolescent Case of Hepatosplenic T-cell Lymphoma
- Affiliations
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- 1Department of Pediatrics, Pusan National University School of Medicine, Busan, Korea. sspark@pusan.ac.kr
- 2Department of Laboratory Medicine, Pusan National University School of Medicine, Busan, Korea.
- 3Department of Pathology, Pusan National University School of Medicine, Busan, Korea.
Abstract
- Hepatosplenic T-cell lymphoma is a rare peripheral T-cell lymphoma, which is associated with an aggressive and fatal course. We described the case of hepatosplenic T-cell lymphoma in a 17-year-old boy who presented with fever for 2 months and marked splenomegaly. The biopsy of bone marrow and spleen were diagnostic of hepatosplenic T-cell lymphoma. He was treated with multi-agent chemotherapy composed of cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate and cytarabine without stem cell transplantation. The patient is currently alive and has remained in remission for 22 months after the diagnosis of his disease and a follow-up period of 15 months from an end of treatment.
MeSH Terms
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Adolescent
Biopsy
Bone Marrow
Cyclophosphamide
Cytarabine
Dexamethasone
Doxorubicin
Fever
Follow-Up Studies
Humans
Lymphoma, T-Cell
Lymphoma, T-Cell, Peripheral
Methotrexate
Spleen
Splenomegaly
Stem Cell Transplantation
T-Lymphocytes
Vincristine
Cyclophosphamide
Cytarabine
Dexamethasone
Doxorubicin
Methotrexate
Vincristine
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